By Dr. Pascal Sacré |
Global Research, November 05, 2020 |
It is time for everyone to come out of this negative trance, this collective hysteria, because famine, poverty, massive unemployment will kill, mow down many more people than SARS-CoV-2!
Introduction: using a technique to lock down society
All current propaganda on the COVID-19 pandemic is based on an assumption that is considered obvious, true and no longer questioned:
Positive RT-PCR test means being sick with COVID. This assumption is misleading.
Very few people, including doctors, understand how a PCR test works.
RT-PCR means Real Time-Polymerase Chain Reaction.
In French, it means: Réaction de Polymérisation en Chaîne en Temps Réel.
In medicine, we use this tool mainly to diagnose a viral infection.
Starting from a clinical situation with the presence or absence of particular symptoms in a patient, we consider different diagnoses based on tests.
In the case of certain infections, particularly viral infections, we use the RT-PCR technique to confirm a diagnostic hypothesis suggested by a clinical picture.
We do not routinely perform RT-PCR on any patient who is overheated, coughing or has an inflammatory syndrome!
It is a laboratory, molecular biology technique of gene amplification because it looks for gene traces (DNA or RNA) by amplifying them.
In addition to medicine, other fields of application are genetics, research, industry and forensics.
The technique is carried out in a specialized laboratory, it cannot be done in any laboratory, even a hospital. This entails a certain cost, and a delay sometimes of several days between the sample and the result.
Today, since the emergence of the new disease called COVID-19 (COrona VIrus Disease-2019), the RT-PCR diagnostic technique is used to define positive cases, confirmed as SARS-CoV-2 (coronavirus responsible for the new acute respiratory distress syndrome called COVID-19).
These positive cases are assimilated to COVID-19 cases, some of whom are hospitalized or even admitted to intensive care units.
Official postulate of our managers: positive RT-PCR cases = COVID-19 patients. [1]
This is the starting postulate, the premise of all official propaganda, which justifies all restrictive government measures: isolation, confinement, quarantine, mandatory masks, color codes by country and travel bans, tracking, social distances in companies, stores and even, even more importantly, in schools [2].
This misuse of RT-PCR technique is used as a relentless and intentional strategy by some governments, supported by scientific safety councils and by the dominant media, to justify excessive measures such as the violation of a large number of constitutional rights, the destruction of the economy with the bankruptcy of entire active sectors of society, the degradation of living conditions for a large number of ordinary citizens, under the pretext of a pandemic based on a number of positive RT-PCR tests, and not on a real number of patients.
Technical aspects: to better understand and not be manipulated
The PCR technique was developed by chemist Kary B. Mullis in 1986. Kary Mullis was awarded the Nobel Prize in Chemistry in 1993.
Although this is disputed [3], Kary Mullis himself is said to have criticized the interest of PCR as a diagnostic tool for an infection, especially a viral one.
He stated that if PCR was a good tool for research, it was a very bad tool in medicine, in the clinic [4].
Mullis was referring to the AIDS virus (HIV retrovirus or HIV) [5], before the COVID-19 pandemic, but this opinion on the limitation of the technique in viral infections [6], by its creator, cannot be dismissed out of hand; it must be taken into account!
PCR was perfected in 1992.
As the analysis can be performed in real time, continuously, it becomes RT (Real-Time) – PCR, even more efficient.
It can be done from any molecule, including those of the living, the nucleic acids that make up the genes:
- DNA (deoxyribonucleic acid)
- RNA (Ribonucleic Acid)
Viruses are not considered as “living” beings, they are packets of information (DNA or RNA) forming a genome.
It is by an amplification technique (multiplication) that the molecule sought is highlighted and this point is very important.
RT-PCR is an amplification technique [7].
If there is DNA or RNA of the desired element in a sample, it is not identifiable as such.
This DNA or RNA must be amplified (multiplied) a certain number of times, sometimes a very large number of times, before it can be detected. From a minute trace, up to billions of copies of a specific sample can be obtained, but this does not mean that there is all that amount in the organism being tested.
In the case of COVID-19, the element sought by RT-PCR is SARS-CoV-2, an RNA virus [8].
There are DNA viruses such as Herpes and Varicella viruses.
The most well known RNA viruses, in addition to coronaviruses, are Influenza, Measles, EBOLA, ZIKA viruses.
In the case of SARS-CoV-2, RNA virus, an additional specific step is required, a transcription of RNA into DNA by means of an enzyme, Reverse Transcriptase.
This step precedes the amplification phase.
It is not the whole virus that is identified, but sequences of its viral genome.
This does not mean that this gene sequence, a fragment of the virus, is not specific to the virus being sought, but it is an important nuance nonetheless:
RT-PCR does not reveal any virus, but only parts, specific gene sequences of the virus.
At the beginning of the year, the SARS-CoV-2 genome was sequenced.
It consists of about 30,000 base pairs. The nucleic acid (DNA-RNA), the component of the genes, is a sequence of bases. In comparison, the human genome has more than 3 billion base pairs.
Teams are continuously monitoring the evolution of the SARS-CoV-2 viral genome as it evolves [9-10-11], through the mutations it undergoes. Today, there are many variants [12].
By taking a few specific genes from the SARS-CoV-2 genome, it is possible to initiate RT-PCR on a sample from the respiratory tract.
For COVID-19 disease, which has a nasopharyngeal (nose) and oropharyngeal (mouth) entry point, the sample should be taken from the upper respiratory tract as deeply as possible in order to avoid contamination by saliva in particular.
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